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Over-connected hubs in MetaCore (Transcription Regulation algorithm) resulted in a largely similar list of transcription factors for Oikopleura and human BaP-regulated gene sets (Additional file 6, not shown). Not surprisingly, AhR was in the human list of transcription factor networks (not shown), but not in the Oikopleura list, suggesting lack of modulated AhR target genes in the latter. Another
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Unol 2003, 171:955-963. Laichalk LL, Kunkel SL, Strieter RM, Danforth JM, Bailie MB, Standiford TJ: Tumor necrosis factor mediates lung antibacterial host defense in murine Klebsiella pneumonia. Infect Immun 1996, 64:5211-5218. Markart P, Korfhagen TR, Weaver TE, Akinbi HT: Mouse lysozyme M is important in pulmonary host defense against Klebsiella pneumoniae infection. Am J Respir Crit Care Med 20
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11:156-160)Schizophrenia and most other forms of serious mental illness have11:156-160)Schizophrenia and most other forms of serious mental illness have traditionally been viewed as chronic conditions with poor outcomes. This pessimistic view has begun to change, as a series of long-term outcome studies have demonstrated that the course is more variable both across and within individuals, an
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Outcome, with substantial reduction of symptoms, and good quality of lifeOutcome, with substantial reduction of symptoms, and good quality of life and role function over extended periods of time. At the same time as these new outcome data have been collected, there is growing recognition that traditional paternalistic mental health services have generated feelings of hopelessness and helples